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Obesity raises migraine risk dramatically — and weight loss helps

basic-science healthcare stress-management

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People who are morbidly obese (roughly a BMI of 35 or above) face five times the risk of developing more frequent migraines compared to people at a healthy weight, and those who are obese (BMI 30–35) face roughly double the risk. Brian Grosberg explains that migraine has a pro-inflammatory component to its underlying biology, and obesity likely shares overlapping inflammatory mechanisms that drive this association. Studies examining both surgical and non-surgical weight loss have shown improvement in migraine frequency, though not uniformly across all patients. Grosberg places obesity alongside sleep disturbance, mood disorders, and frequent use of pain medications as modifiable risk factors that, if addressed, can reduce how often migraines occur and slow the progression from episodic to chronic migraine.

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