A randomized controlled trial published in the journal *Current Developments in Nutrition* in April 2026 found no difference between organic and synthetic multivitamin-and-mineral supplements in raising blood levels of vitamins and minerals. The study gave 62 healthy adults either an organic or synthetic supplement for 30 days, with each supplement providing 60 percent of the recommended dietary allowance for five vitamins (B12, biotin, C, D3, and folate) and six minerals (calcium, chromium, iodine, iron, selenium, and zinc). Researchers measured blood levels before the 30-day period, two hours after the first dose, and at the end of the study.
According to the study, whether a multivitamin-and-mineral supplement is labeled organic or synthetic did not affect how much it raised participants' blood levels of those nutrients. Organic supplements are generally priced higher than synthetic ones, though the study did not address cost.
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